بررسی روند تغییرات بروز سرطان معده در ایران

Background and purpose: Cancer is a major cause of death worldwide and gastric cancer with high mortality rate is one of the leading causes of cancer-related death. Understanding the epidemiology of gastric cancer could be of great benefit. However, no clear trend is available on incidence of this cancer in Iran, therefore, this study aimed at investigating the incidence of gastric cancer. Material and Methods: Data included the records from the cancer registry system in Iran during 2003 to 2009. The incidence rates were then standardized using direct method. Results: We found an increasing trend during 2003 to 2009 in Iran. A total of 42,135 cases with gastric cancer were reported of which 4254 were recorded in 2003. However, this rate increased to 6886 cases in 2009. The highest and lowest rate of stomach cancer in male and female were observed in 2008 and 2003, respectively. The sex ratio was 2.51 in these years. Different regions in Iran were found with different rates of incidence. Men and women were more prone to suffer from gastric cancer in Ardabil and Semnan provinces, respectively. While the least number of diagnosed male were recorded in Kohkilooyeh Boyer Ahmad. Also, the incidences of gastric cancer were lowest in female living in Kohkilooyeh Boyer Ahmad and Hormozgan provinces Conclusion: : According to this study the prevalence of gastric cancer is increasing in northern and western regions of Iran. This could be caused by diet and Helicobacter pylori infection, hence, screening and early detection programs are highly recommended in high-risk areas.